Key result
Insulin resistance in normotensive women was associated with an exaggerated systolic blood pressure response to mental stress compared to healthy controls (18% vs 10%, P<0.01).
Why the study?
Does insulin resistance alter hemodynamic and vascular reactivity responses to mental and physical stress in normotensive women?
Observational (n=20)
Does insulin resistance alter hemodynamic and vascular reactivity responses to mental and physical stress in normotensive women?
Absolute Event Rate: 18% vs 10%
p-value: p=<0.01
Insulin resistance in moderately obese, normotensive women is associated with abnormal vasoconstriction and exaggerated blood pressure responses to stress, which may serve as an early marker for future hypertension.
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IR may impair vascular stress responses in normotensive women; leaves open causal role in hypertension.
Sung et al. (1997) conducted an observational in Insulin resistance (n=20). Insulin resistance vs. Healthy normotensive women with normal glucose tolerance was evaluated on Increase in systolic blood pressure in response to mental stress (p=<0.01). Insulin resistance in normotensive women was associated with an exaggerated systolic blood pressure response to mental stress compared to healthy controls (18% vs 10%, P<0.01).
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