Key result
Left atrial function parameters measured by 2D-STE and RT-3DE differed significantly between patients with varying severities of triple-vessel coronary artery disease and healthy controls.
Why the study?
To evaluate left atrial function in patients with triple-vessel coronary artery disease without myocardial infarction using RT-3DE and 2D-STE.
Can real-time three-dimensional echocardiography and two-dimensional speckle tracking imaging effectively evaluate left atrial function and correlate with LVEDP and NT-pro-BNP in patients with triple-vessel coronary artery disease without myocardial infarction?
Observational (n=90)
Can real-time three-dimensional echocardiography and two-dimensional speckle tracking imaging effectively evaluate left atrial function and correlate with LVEDP and NT-pro-BNP in patients with triple-vessel coronary artery disease without myocardial infarction?
RT-3DE and 2D-STE can effectively assess left atrial dysfunction in patients with triple-vessel disease without prior MI, with strain values correlating with LVEDP and NT-pro-BNP.
Answers are grounded in this paper and cite their sources.
Supports noninvasive LA assessment in triple-vessel CAD; hypothesis-generating pending prospective validation against hemodynamics and outcomes.
OBJECTIVE: To evaluate left atrial function in patients with triple-vessel disease (TVD) without myocardial infarction by real-time three-dimensional echocardiography (RT-3DE) and two-dimensional speckle tracking imaging (2D-STE). METHODS: Sixty patients with coronary artery disease (CAD) without myocardial infarction were classified into two groups in accordance with the coronary angiography results: group B (all triple-vessel stenosis ≥ 50% and < 75%) and group C (all triple-vessel stenosis ≥ 75%). Thirty healthy individuals were selected as group A. LA volume related parameters including left atrial maximum volume index (LAVImax), LA passive and active ejection fraction (LAPEF, LAAEF) and LA total ejection fraction (LATEF) were measured by RT-3DE. The global peak atrial longitudinal systolic strain (LASRs), early and late diastolic LA strain (LASRe and LASRa) rates were measured by 2D-STE. RESULTS: We found statistically significant differences between 2D-STE and RT-3DE related parameters of these three groups. Furthermore, in groups B and C, N-terminal fragment brain natriuretic peptides (NT-pro-BNP) and left ventricular end-diastolic pressure (LVEDP) were found to be significantly correlated with LASRs and LASRa. And NT-pro-BNP had a moderate correlation with LVEDP. CONCLUSIONS: 2D-STE and RT-3DE can assess the LA function in patients with TVD without myocardial infarction. And LA strain values may provide additional information for predicting increased LVEDP and NT-pro-BNP.
No takes yet. Share an insight, caveat, or question.
Yu et al. (2022) conducted an observational in Triple-vessel coronary artery disease without myocardial infarction (n=90). Triple-vessel coronary artery disease vs. Healthy controls was evaluated on Left atrial function parameters measured by RT-3DE and 2D-STE. Left atrial function parameters measured by 2D-STE and RT-3DE differed significantly between patients with varying severities of triple-vessel coronary artery disease and healthy controls.
Synapse has enriched 10 related papers. Consider them for comparative context: