Key result
Severe structural valve deterioration occurred in 5.9% of patients overall, but was more frequent with balloon-expandable than self-expanding valves (11.9% vs. 3.5%; p=0.02).
Why the study?
With expansion of TAVI into younger patients, valve durability is critically important.
Does valve type (self-expanding vs balloon-expandable) affect long-term structural valve deterioration in patients undergoing TAVI?
Population
221 patients undergoing TAVI with paired echocardiograms postprocedure and ≥5-years post-TAVI
Comparison
Self-expanding vs balloon-expandable transcatheter heart valves
Design
Registry-based cohort study
Follow-up
Median 7.0 years (range 5-13 years)
Authors
Loading...
Severe SVD may differ by valve type after TAVI; leaves open durability questions requiring randomized confirmation before practice change.
Cohort (n=221)
Yes
Does valve type (self-expanding vs balloon-expandable) affect long-term structural valve deterioration in patients undergoing TAVI?
Absolute Event Rate: 11.9% vs 3.5%
p-value: p=0.02
Transcatheter heart valves demonstrate stable hemodynamic function up to 10 years post-procedure, with severe structural valve deterioration occurring in 5.9% of patients, more commonly in those with balloon-expandable valves.
Ali et al. (2023) conducted a cohort in Transcatheter aortic valve implantation (TAVI) (n=221). Balloon-expandable valves (BEV) vs. Self-expanding valves (SEV) was evaluated on Severe structural valve deterioration (SVD) (p=0.02). Severe structural valve deterioration occurred in 5.9% of patients overall, but was more frequent with balloon-expandable than self-expanding valves (11.9% vs. 3.5%; p=0.02).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: