Key result
Anxiolytic therapy with diazepam in patients with hypertensive urgency resulted in a greater reduction in systolic blood pressure compared to treatment without anxiolytics.
Why the study?
Current guidelines do not cover hypertensive urgency management in an out-of-hospital setting, prompting an evaluation of anxiolytic therapy in these patients.
Does anxiolytic therapy improve systolic blood pressure reduction in patients with hypertensive urgency in an out-of-hospital setting?
Observational (n=144)
No
Does anxiolytic therapy improve systolic blood pressure reduction in patients with hypertensive urgency in an out-of-hospital setting?
Anxiolytic therapy may be a beneficial adjunct for managing hypertensive urgency in out-of-hospital settings, leading to greater reductions in systolic blood pressure.
Answers are grounded in this paper and cite their sources.
May support anxiolytics as adjunct in out-of-hospital hypertensive urgency; leaves open need for RCTs before practice change.
Current guidelines do not cover hypertensive urgency management in out-of-hospital setting. Main goal of this study was to evaluate the value of anxiolytic therapy in hypertensive urgencies. We analyzed data gathered by out-of-hospital unit set up during one year. Arterial hypertension was the primary diagnosis in 178 (6.11%) patients, of whom 144 had hypertensive urgency with mean SBP reduction 19.5±7.2%; control group 10.1±6.9%. Anxiolytic therapy was administered in 60% of patients in hypertensive urgency group, and they had a statistically significant greater SBP reduction (p=0.03) than patients who did not receive anxiolytic therapy. There is a place for anxiolytic therapy in hypertensive urgency management.
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Paštrović et al. (2020) conducted an observational in Hypertensive urgency (n=144). Anxiolytic therapy (diazepam) vs. Treatment without anxiolytics was evaluated on Percentage reduction in systolic blood pressure (SBP) (p=0.03). Anxiolytic therapy with diazepam in patients with hypertensive urgency resulted in a greater reduction in systolic blood pressure compared to treatment without anxiolytics.
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