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August 1, 2026Gut Microbes ReportsOpen Access

Isolation and characterization of a novel lytic bacteriophage for Faecalibacterium prausnitzii, a key member of the human gut microbiota

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Randomized trial investigates lytic bacteriophage dynamics in gut microbiota, suggesting implications for microbial health.

The aim is to isolate and characterize a novel lytic bacteriophage for Faecalibacterium prausnitzii, enhancing understanding of gut microbiota dynamics.
Isolation of lytic phage vB_Fpr_FP01 targeting F. prausnitzii
Whole-genome sequencing and comparative genomics analysis
Identification of related viral sequences in human gut virome dataset.
Novel lytic bacteriophage vB_Fpr_FP01 was successfully isolated and characterized.
Whole-genome analysis showed FP01 as a distinct species within the Caudovirales class.
Related phage sequences were identified in gut-associated environments.

Whitty et al. (2026) studied this question.

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