Investigates the role of metabotropic glutamate receptor 5 in synaptic upscaling, suggesting crucial implications for nervous system function.
In the mammalian nervous system, synaptic transmission depends on the interplay between reliable signaling and dynamic tunability, a balance achieved through synaptic plasticity. One way this plasticity is mediated is by classical Hebbian mechanisms, in which correlated pre- and postsynaptic
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Arefin et al. (2026) studied this question.
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