Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 1, 2026BMC PsychiatryOpen Access

Plasma chromogranin a levels and their role in the etiology of anxiety disorders in children and adolescents

View Full Paper
Ask AI
Bookmark
Share

Authors

ÇTÇiğdem TanrıverdiBBBürge Kabukçu BaşayİKİhsan Kara

Discussion

Loading...

Member takes

Overview

Cross-sectional study analyzes plasma CgA levels in children and adolescents with anxiety disorders, suggesting developmental differences from adults.

Key Points

  • This research aims to investigate plasma chromogranin A concentrations in medication-naïve children and adolescents diagnosed with anxiety disorders.
  • Cross-sectional study with 37 medication-naïve children and adolescents aged 9–18 years diagnosed with anxiety disorders and 34 controls.
  • Plasma chromogranin A concentrations measured using enzyme-linked immunosorbent assay (ELISA).
  • SCARED Parent Form completed by parents to assess anxiety levels.
  • Total and subscale SCARED scores were significantly higher in the anxiety disorder group compared to controls (p < 0.001).
  • No significant differences in plasma CgA levels between anxiety disorder and control groups (p > 0.05).
  • Family structure differed significantly between groups (p = 0.012).

Cite This Study

Tanrıverdi et al. (2026) studied this question.

synapsesocial.com/papers/6a6d985be258b358b3c6b8d8https://doi.org/10.1186/s12888-026-08457-4
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical and autonomic functions: a study of childhood anxiety disorders2011 · 16 citations
  2. 2Salivary chromogranin a reflects autonomic regulation during “wake to sleep” and “sleep to wake” transitions2025
  3. 3Exploring volumetric abnormalities in subcortical L-HPA axis structures in pediatric generalized anxiety disorder2024 · 1 citations
  4. 4Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function2007 · 164 citations
  5. 5Hsp70 and Hsp90 as Molecular Correlates of Anxiety in Children and Adolescents: The Role of Early‐Life Stress2025