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August 1, 2026Acta Neurologica TaiwanicaOpen Access

Microbleeds as a Causative Factor in Diffusion-Weighted Imaging–Negative Acute Brainstem Stroke Syndrome: A Report of Three Cases

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Authors

CLChi-Ju LinCLChun-Jen LinCCChih-Ping Chung

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Overview

Case report reveals microbleeds as a possible cause of acute brainstem syndrome in patients with negative DWI findings, suggesting new diagnostic considerations.

Key Points

  • To investigate the role of cerebral microbleeds in patients with acute brainstem stroke presenting with negative DWI findings.
  • Three cases of acute brainstem syndrome assessed for cause of neurological deficits despite negative DWI on MRI.
  • Neurological examinations documented symptoms including diplopia, dizziness, ataxia, and facial palsy.
  • Cerebral microbleeds identified in relation to detected deficits.
  • CMBs corresponded to the neurological deficits observed in each patient.
  • All patients recovered significant symptoms within 7 days.
  • Highlights the need for including CMBs in the differential diagnosis of posterior circulation stroke syndromes.

Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/6a6d9892e258b358b3c6c262https://doi.org/10.4103/ant.ant-d-25-00024
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