Key result
Older age was associated with increased 30-day mortality following emergency colectomy, with rates rising from 3.2% in patients aged 18-59 years to 37.8% in those aged ≥80 years.
Why the study?
Emergency colonic resections among the aging population are increasing, but data regarding short- and long-term outcomes in this population remain scarce.
Does older age increase perioperative mortality and affect long-term survival in patients undergoing emergent colectomies?
Cohort (n=613)
No
Does older age increase perioperative mortality and affect long-term survival in patients undergoing emergent colectomies?
Absolute Event Rate: 37.8% vs 3.2%
Perioperative mortality following emergency colectomy increases significantly with age, reaching 37.8% in patients aged 80 years and older.
Age-specific risks after emergent colectomy remain uncertain; leaves open need for prospective data before changing thresholds.
BACKGROUND: As the population ages emergency surgeries among the elderly population, including colonic resections, is also increasing. Data regarding the short- and long-term outcomes in this population is scarce. METHODS: A retrospective study was performed to investigate mortality and mortality risk factors associated with emergent colectomies in older compared to younger patients in a single university affiliated tertiary hospital. Patients with metastatic disease, colectomy due to trauma or index colectomy within 30 days prior to emergent surgery were excluded. RESULTS: Operative outcomes compared among age groups, included 30-day mortality, mortality risk-factors and long-term survival. 613 eligible patients were included in the cohort. Mean age was 69.4 years, 45.1% were female. Patients were divided into four age groups: 18-59, 60-69, 70-79 and ≥80-years. Thirty-day mortality rates were 3.2%, 11%, 29.3% and 37.8%, respectively and 22% for the entire cohort. Risk-factors for perioperative death in the younger group were related to severity of ASA score and WBC count. In groups 60-69, 70-79, main risk-factors were ADL dependency and ASA score. In the ≥80 group, risk-factors affecting perioperative mortality, included ASA score, pre-operative albumin, creatinine, WBC levels, cancer etiology, ADL dependency, and dementia. Long-term survival differed significantly between age groups. CONCLUSION: Perioperative mortality with emergency colectomy increases with patients' age. Patients older than eighty-years undergoing urgent colectomies have extremely high mortality rates, leading to a huge burden on medical services. Evaluating risk-factors for mortality and pre-operative discussion with patients and families is important. Screening the elderly population for colonic pathologies can result in early diagnosis potentially leading to elective surgeries with decreased mortality.
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Kent et al. (2023) conducted a cohort in Emergency colectomy (n=613). Older age vs. Younger age was evaluated on 30-day mortality. Older age was associated with increased 30-day mortality following emergency colectomy, with rates rising from 3.2% in patients aged 18-59 years to 37.8% in those aged ≥80 years.