Key result
Among patients undergoing transcatheter aortic valve replacement, the presence of CKD or ESRD was associated with significantly greater in-hospital mortality compared to no CKD/ESRD (P<0.001).
Why the study?
Does the presence of CKD or ESRD increase in-hospital mortality and adverse events in patients undergoing TAVR?
Population
42,189 patients undergoing transcatheter aortic valve replacement in the United States between 2011 and 2014.
Comparison
Presence of chronic kidney disease or end-stage… vs Patients with no CKD/ESRD
Design
Cohort
Follow-up
In-hospital
Authors
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CKD/ESRD associated with higher TAVR mortality and complications; leaves open whether targeted renal strategies improve outcomes.
Cohort (n=42,189)
Yes
Does the presence of CKD or ESRD increase in-hospital mortality and adverse events in patients undergoing TAVR?
p-value: p=<0.001
In patients undergoing TAVR, the presence of CKD or ESRD is associated with significantly higher in-hospital mortality and periprocedural complications compared to patients with normal renal function.
Mohananey et al. (2017) conducted a cohort in Aortic stenosis undergoing transcatheter aortic valve replacement (n=42,189). Chronic kidney disease (CKD) or end-stage renal disease (ESRD) vs. No CKD/ESRD was evaluated on In-hospital mortality (p=<0.001). Among patients undergoing transcatheter aortic valve replacement, the presence of CKD or ESRD was associated with significantly greater in-hospital mortality compared to no CKD/ESRD (P<0.001).
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