Key result
Hybrid TAV-in-TAV with off-pump CABG succeeds without complications in a high-risk coronary obstruction case.
Why the study?
Few reports have described TAV-in-TAV with simultaneous surgical coronary revascularization to prevent coronary obstruction in patients unsuitable for conventional transcatheter preventive techniques.
Does a hybrid strategy of TAV-in-TAV with concomitant OPCAB prevent coronary obstruction in a patient with high anatomical risk?
Case Report (n=1)
No
Does a hybrid strategy of TAV-in-TAV with concomitant OPCAB prevent coronary obstruction in a patient with high anatomical risk?
Answers are grounded in this paper and cite their sources.
A surgical-transcatheter hybrid strategy combining TAV-in-TAV with OPCAB is a feasible approach for preventing coronary obstruction in anatomically high-risk patients unsuitable for conventional transcatheter preventive techniques.
We report a case of a 90-year-old woman with prior transcatheter aortic valve replacement (TAVR) who presented with symptomatic structural valve deterioration. Imaging revealed a critically short valve-to-coronary distance (< 4 mm), suggesting a high risk for coronary obstruction during valve-in-valve (TAV-in-TAV) procedure. Although preventive techniques such as BASILICA and chimney stenting have been considered, these approaches require advanced technical expertise and are associated with procedural risks. Given the patient's advanced age and high surgical risk, we therefore opted for a hybrid strategy combining TAV-in-TAV with concomitant off-pump coronary artery bypass grafting to the left anterior descending artery for coronary protection. The procedure was successfully completed without complications. Postoperative imaging confirmed good prosthetic valve function, graft patency, and preserved coronary flow. To our knowledge, few reports have described TAV-in-TAV with simultaneous surgical coronary revascularization as a preventive approach for coronary obstruction. This case highlights the potential utility of surgical–transcatheter hybrid strategy in anatomically high-risk patients unsuitable for conventional transcatheter preventive techniques.
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fuwa et al. (2026) conducted a case report in Symptomatic structural valve deterioration post-TAVR with high risk of coronary obstruction (n=1). TAV-in-TAV with concomitant off-pump coronary artery bypass (OPCAB) was evaluated on Procedural success and prevention of coronary obstruction. A hybrid strategy combining TAV-in-TAV with concomitant off-pump coronary artery bypass grafting was successfully performed without complications in a 90-year-old woman at high risk for coronary obstruction.
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