Key result
Simultaneous transaortic TAVI and OPCAB results in 0 hospital deaths or on-pump conversions in high-risk patients.
Why the study?
Is simultaneous transaortic TAVI and OPCAB feasible and safe in high-risk patients with severe AS and IHD?
Observational (n=12)
No
Is simultaneous transaortic TAVI and OPCAB feasible and safe in high-risk patients with severe AS and IHD?
Simultaneous transaortic TAVI and OPCAB is a feasible and safe alternative to surgical aortic valve replacement and CABG in high-risk patients with severe AS and complex IHD.
Answers are grounded in this paper and cite their sources.
Should not yet change practice in high-risk AS and IHD; hypothesis-generating case experience requiring prospective validation.
BACKGROUND: Transcatheter aortic valve implantation (TAVI) has become an alternative procedure for treating aortic stenosis (AS) in patients with advanced age and severe comorbidities. Ischemic heart disease (IHD) is present with AS in 40-50% of patients with typical angina. Considering the high operative mortality and morbidity rates in these patients, hybrid TAVI and off-pump CABG (OPCAB) have become realistic treatment options. METHODS AND RESULTS: Between August 2014 and November 2015, 12 patients were evaluated for simultaneous TAVI and OPCAB. Because of their advanced age and comorbidities these patients were not considered suitable for standard open heart surgery. PCI was also considered unsuitable, because of left anterior descending artery (LAD) proximal lesions and/or high SYNTAX score. TAVI was conducted through a median sternotomy after left internal thoracic artery (LITA) to LAD anastomosis. In 11 cases OPCAB with LITA and composite RA graft was performed using an aorta no-touch technique. Mean age at operation was 81±6.3 years. Average number of distal anastomoses was 2.6. Perivalvular leakage was mild in 3 patients, trivial in 8, and none in 1. There was no conversion to on-pump procedure and no hospital deaths. CONCLUSIONS: Simultaneous transaortic TAVI and OPCAB in high-risk patients with severe AS and IHD is a reasonable option. This method could be an alternative to surgical aortic valve replacement and CABG. (Circ J 2016; 80: 1946-1950).
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Kobayashi et al. (2016) conducted an observational in Severe aortic stenosis and ischemic heart disease (n=12). Simultaneous transaortic TAVI and OPCAB was evaluated on Hospital deaths and conversion to on-pump procedure. Simultaneous transaortic TAVI and total arterial off-pump coronary artery bypass grafting resulted in no hospital deaths or conversions to on-pump procedures among 12 high-risk patients.
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