What question did this study set out to answer?

Evaluate the influence of different analyzers, sampling methods, ventilation estimates, body postures, and mathematical formulas on the precision of the optimized carbon monoxide rebreathing method.

November 1, 2011European Journal of Sport Science

Precision of the optimized carbon monoxide rebreathing method to determine total haemoglobin mass and blood volume

View Full Paper

Ask AI

Bookmark

Evaluate the influence of different analyzers, sampling methods, ventilation estimates, body postures, and mathematical formulas on the precision of the optimized carbon monoxide rebreathing method.
Measured total haemoglobin mass twice on consecutive days in 11 subjects using both venous and capillary blood sampling.
Compared two portable carbon monoxide analysers (Fluke CO-220 vs Pac 7000 Draeger) and automated metabolic measurement vs estimation of alveolar ventilation.
Assessed blood volume derived in supine versus seated body positions and compared two different calculation formulas.
Total haemoglobin mass measurements demonstrated high day-to-day precision (typical error < 2%), with no significant differences between the Fluke (917±136 g) and Draeger analyzer (904±137 g; mean bias -13 g, P=0.76), ventilation estimation methods (mean bias -6 g, P=0.87), or capillary vs venous blood (mean bias 0 g, P=0.99).
Blood volume estimates were unaffected by supine versus seated body posture (6.7±0.8 L vs 6.6±0.8 L, P=0.56) but significantly deviated by ~0.6 L depending on the calculation formula used (P=0.01).

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Validation study demonstrates high measurement precision for carbon monoxide rebreathing in healthy adults, indicating consistent calculation formulas are essential for longitudinal tracking.

Cite This Study

Durussel et al. (2011) studied this question.

synapsesocial.com/papers/6a6da922febe604dd707c99f https://doi.org/10.1080/17461391.2011.606843

View Full Paper

Ask AI

Bookmark

Implication

Validation study demonstrates high measurement precision for carbon monoxide rebreathing in healthy adults, indicating consistent calculation formulas are essential for longitudinal tracking.

Precision of the optimized carbon monoxide rebreathing method to determine total haemoglobin mass and blood volume

Key Points

Discussion

Implication

Cite This Study

Precision of the optimized carbon monoxide rebreathing method to determine total haemoglobin mass and blood volume

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider