Key result
Nonemergent, nonneurological, noncardiac, nonvascular surgery within 3 months after a stroke is associated with a 153-fold risk of postoperative stroke and a 12-fold risk of in-hospital mortality.
Why the study?
To evaluate postoperative stroke and mortality in patients with a history of stroke and provide a framework for perioperative care in an elective setting.
Does the time elapsed since a recent stroke affect the risk of postoperative stroke and mortality in patients undergoing nonemergent, nonneurological, noncardiac, nonvascular surgery?
Population
Patients with a history of stroke undergoing nonemergent, nonneurological, noncardiac, nonvascular surgery
Comparison
Surgery at different time intervals after stroke vs later surgery or baseline risk
Design
Systematic review and meta-analysis
Authors
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May warrant delaying elective surgery after recent stroke; leaves open optimal timing in prospective trials.
Meta-Analysis
Does the time elapsed since a recent stroke affect the risk of postoperative stroke and mortality in patients undergoing nonemergent, nonneurological, noncardiac, nonvascular surgery?
Effect estimate: 153-fold risk
Recent stroke drastically increases the risk of postoperative stroke and mortality, emphasizing the need to delay elective noncardiac, nonneurological surgery when possible and individualize perioperative care.
Lele et al. (2024) conducted a meta-analysis in History of stroke undergoing nonemergent, nonneurological, noncardiac, nonvascular surgery. Surgery within 3 months after stroke was evaluated on Postoperative stroke (153-fold risk). Nonemergent, nonneurological, noncardiac, nonvascular surgery within 3 months after a stroke is associated with a 153-fold risk of postoperative stroke and a 12-fold risk of in-hospital mortality.
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