Key result
Physical inactivity is linked to ~3.5-fold higher odds of tranquilizer use in hypertensive adults.
Why the study?
Hypertension is highly prevalent and affects mental health, while physical activity improves mental health, but their specific associations in hypertensive individuals required evaluation.
Does physical inactivity increase the risk of depression, anxiety, and related medication use in adults with hypertension?
Cross-Sectional (n=3,228)
Does physical inactivity increase the risk of depression, anxiety, and related medication use in adults with hypertension?
Odds Ratio: 3.5 (95% CI 2.22–5.51)
p-value: p=<0.001
Physical inactivity is strongly associated with higher rates of depression, anxiety, and psychoactive medication use among hypertensive patients, reinforcing the role of exercise in comprehensive cardiovascular risk management.
Hypertension (HTN) has a high prevalence in the overall population, affecting people’s mental health. Physical Activity (PA) has proven to be an effective tool to improve mental health. This study analyzed the associations between Depression and Anxiety prevalence, medication use for these disorders (antidepressants and anxiolytics) and Physical Activity Level (PAL) in people with HTN. A cross-sectional study was conducted with data from the Spanish National Health Survey 2017 (ENSE2017) with a final sample of 3228 individuals over 15 years of age with HTN who resided in Spain. Data normality was assessed through the Kolmogorov–Smirnov test. Associations between Depression and Anxiety prevalence, antidepressant and anxiolytic use and PAL were studied using a chi-square test. Possible differences between Depression and Anxiety prevalence and medication use according to the PAL were analyzed with a z-test for independent proportions. Depression or Anxiety and antidepressant and anxiolytic use odds ratios (OR) were calculated for every PAL group, taking the “Very Active” group as a reference. Risk factors were evaluated using multiple binary logistic regression. Dependency relationships were found between Depression and Anxiety prevalence, antidepressant and anxiolytic use and PAL (p < 0.001). The Inactive group displayed the highest prevalence and medication use according to their PAL (p < 0.05). Higher ORs for Depression or Anxiety and pharmacological treatments used were also found in the Inactive group compared to the other PAL groups.
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Denche-Zamorano et al. (2023) conducted a cross-sectional in Hypertension (n=3,228). Physical Inactivity vs. Very Active physical activity level was evaluated on Tranquilizer use (OR 3.50, 95% CI 2.22-5.51, p=<0.001). Physical inactivity significantly increased the odds of using tranquilizers (OR 3.50) and antidepressants compared to being very active among adults with hypertension.
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