Temporal trends of cause-specific mortality after diagnosis of atrial fibrillation

Figures

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  Figure 1. Temporal trends in all-cause and cause-specific mortality rates at 1 year following diagnosis of atrial fibrillation. (A) Crude rate of all-cause and cause-specific mortality following diagnosis of atrial fibrillation. Labels for years 2001–17 present individual causes of death as a share of the total number of deaths at 1 year. (B) Rate ratios from multivariable Poisson regression models comparing 1-year mortality rates in 2016/2017 with 2001/2002 by first reported cause of death, adjusting for patients’ age, sex, socioeconomic status, region, and 18 baseline comorbidities. ‘Other’ refers to any other causes except the pre-defined nine disease categories for cause of death.

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  Figure 2. Temporal trends in all-cause and cause-specific mortality rates at 1 year following diagnosis of atrial fibrillation by age group. Crude mortality rates by age groups alongside rate ratios, 95% confidence intervals, and interaction P-values from multivariable Poisson regression models accounting for year of diagnosis, age (as a continuous variable), sex, socio-economic status, region, and 18 baseline comorbidities. Interaction P-values refer to the interaction between age group (categorized as age < 70, age 70–79, or age ≥ 80 years) and year of diagnosis.

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  Figure 3. Differences in mortality rates 1 year after diagnosis of atrial fibrillation by sex, socio-economic status, and place of diagnosis. Crude mortality rates by each category of sex, socio-economic status, and diagnostic setting alongside rate ratios and 95% confidence intervals from multivariable Poisson regression models accounting for year of diagnosis, age (as a continuous variable), sex, socio-economic status, region, and 18 baseline comorbidities.

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  Figure 4. Temporal trends in all-cause and cause-specific mean number of hospitalizations at 1 year following diagnosis of atrial fibrillation. (A) Crude rate of all-cause and cause-specific hospitalization following diagnosis of atrial fibrillation. Labels for years 2001–17 present individual causes of hospitalization as a share of the total number of hospitalizations at 1 year. (B) Rate ratios from multivariable Poisson regression models comparing 1-year hospitalization rates in 2016/2017 with 2001/2002 by primary cause of admission, adjusting for patients’ age, sex, socio-economic status, region, and 18 baseline comorbidities. ‘Other’ refers to any other causes except the pre-defined 11 disease categories for hospitalizations.