Key result
Positive heart rate turbulence was a strong independent predictor of overall cardiac mortality and fatal arrhythmic events in post-myocardial infarction patients (HR 5.7).
Why the study?
Do positive MMA-TWA and HRT on 24-h Holter ECG predict serious cardiac events in post-myocardial infarction patients?
Population
313 consecutive post-myocardial infarction patients. Key exclusions: chronic atrial fibrillation, implanted…
Comparison
Positive modified moving average T-wave… vs Negative MMA-TWA and/or negative HRT.
Design
Cohort
Follow-up
mean 1,190 ± 441 days
Authors
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MMA-TWA and HRT may refine post-MI risk stratification; leaves open whether they guide therapy or improve outcomes.
Observational (n=313)
No
Do positive MMA-TWA and HRT on 24-h Holter ECG predict serious cardiac events in post-myocardial infarction patients?
Hazard Ratio: 5.7 (95% CI 2.1–15.9)
p-value: p=0.0008
Both MMA-TWA and HRT derived from routine 24-h Holter ECGs are independent predictors of serious cardiac events in post-MI patients, with MMA-TWA more strongly associated with arrhythmic events and HRT with overall cardiac mortality.
Hoshida et al. (2012) conducted an observational in Myocardial Infarction (n=313). Positive heart rate turbulence (HRT) vs. Negative heart rate turbulence was evaluated on Overall cardiac mortality and fatal arrhythmic events (HR 5.7, 95% CI 2.1-15.9, p=0.0008). Positive heart rate turbulence was a strong independent predictor of overall cardiac mortality and fatal arrhythmic events in post-myocardial infarction patients (HR 5.7).
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