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Platelet membrane phenotype plays a crucial role in the pathophysiology of myocardial infarction by participating in blood coagulation, local inflammation, and tissue repair.
Platelet membrane phenotype plays a crucial role in the pathophysiology of acute myocardial infarction, specifically in thrombus formation, inflammation, and tissue repair.
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Platelet membrane phenotype may refine MI thrombus understanding; leaves open biomarker validation in prospective studies.
In acute myocardial infarction patients the injured vascular wall triggers thrombus formation in the damage site. Fibrin fibers and blood cellular elements are the major components of thrombus formed in acute occlusion of coronary arteries. It has been established that the initial thrombus is primarily composed of activated platelets rapidly stabilized by fibrin fibers. This review highlights the role of platelet membrane phenotype in pathophysiology of myocardial infarction. Here, we regard platelet phenotype as quantitative and qualitative parameters of the plasma membrane outer surface, which are crucial for platelet participation in blood coagulation, development of local inflammation and tissue repair.
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Gabbasov et al. (2014) conducted a review in acute myocardial infarction. platelet membrane phenotype was evaluated. Platelet membrane phenotype plays a crucial role in the pathophysiology of myocardial infarction by participating in blood coagulation, local inflammation, and tissue repair.
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