Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 1, 1998Current Opinion in Hematology

The collagen-platelet interaction

View Full Paper
Ask AI
Bookmark
Share

Key result

Collagen-platelet interaction is a two-step process of adhesion and activation involving sequential recognition of distinct receptors, culminating in unique signaling events.

Design

Review

Authors

MBMichael J. BarnesBristol-Myers Squibb (Germany)CKChristopher G. KnightUniversity of WashingtonRFRichard W. FarndaleGeneral / Preventive / Lipids

Discussion

Loading...

Member takes

Implication

May refine future antiplatelet targeting; leaves open clinical translation of collagen-receptor mechanisms.

PICO

P
Population
Hemostasis and thrombosis
I
Intervention / Comparator
Collagen-platelet interaction

Provides a detailed molecular overview of the collagen-platelet interaction, highlighting the sequential roles of specific receptors in adhesion and activation.

Cite This Study

Barnes et al. (1998) conducted a review in Hemostasis and thrombosis. Collagen-platelet interaction was evaluated. Collagen-platelet interaction is a two-step process of adhesion and activation involving sequential recognition of distinct receptors, culminating in unique signaling events.

synapsesocial.com/papers/6a6de80dac440176ef275010https://doi.org/10.1097/00062752-199809000-00002
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Platelet-collagen interaction: is GPVI the central receptor?2003 · 1,163 citations
  2. 2Platelet–collagen interactions: membrane receptors and intracellular signalling pathways1999 · 51 citations
  3. 3Platelet Collagen Receptors2001 · 289 citations
  4. 4Collagen-platelet interactions: recognition and signalling2003 · 50 citations
  5. 5Platelet-Collagen Responses: Molecular Basis and Therapeutic Promise2004 · 71 citations