Key result
Adrenalectomy for suspected pheochromocytoma unexpectedly reveals rare adrenal medullary hyperplasia.
Case Report (n=1)
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Case report reveals adrenal medullary hyperplasia mimicking pheochromocytoma biochemically and clinically, highlighting the need for long-term surveillance.
A 59-year-old woman, a known case of hypertension, was incidentally diagnosed with a large right-sided adrenal mass. Investigations for a functional adrenal lesion resulted in very high preoperative norepinephrine levels. A right adrenalectomy was performed. Histology showed adrenal medullary hyperplasia (AMH). AMH is a rare diagnosis and its incidence is poorly documented in the literature. This is a benign entity which resembles pheochromocytoma (PCC) in both clinical and biochemical manner. AMH is usually bilateral and may occur in isolation or in association with PCC. In fact, some authors consider it to be a precursor to PCC. Thus, these patients need long-term follow-up in view of the risk of development of PCC later.
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Montebello et al. (2020) conducted a case report in Adrenal medullary hyperplasia (n=1). Right adrenalectomy was evaluated on Histological diagnosis. Right adrenalectomy in a 59-year-old woman with a suspected pheochromocytoma revealed adrenal medullary hyperplasia, a rare benign condition requiring long-term follow-up.
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