Key result
Plication of posterior leaflet segment 2 in addition to ring annuloplasty resulted in 91.9% medium-term survival and 89.6% freedom from moderate or severe mitral regurgitation.
Why the study?
Does posterior leaflet segment 2 plication in addition to ring annuloplasty improve medium-term outcomes and echocardiographic parameters in patients with functional ischemic mitral regurgitation?
Cohort (n=136)
Does posterior leaflet segment 2 plication in addition to ring annuloplasty improve medium-term outcomes and echocardiographic parameters in patients with functional ischemic mitral regurgitation?
Posterior leaflet segment 2 plication added to ring annuloplasty significantly improves echocardiographic parameters and provides high freedom from moderate or severe mitral regurgitation in the medium term.
P2 plication plus annuloplasty may aid ischemic MR repair; leaves open need for RCTs to confirm durability.
AIM: To evaluate the medium-term results of plication of posterior leaflet segment 2 in addition to ring annuloplasty in patients with functional ischemic mitral regurgitation. METHODS: The study included 136 patients who underwent mitral valve repair with plication of posterior leaflet segment 2 for ischemic mitral regurgitation between 2004 and 2012. The direction and correlation of left ventricle sphericity and tethering area were established by Pearson correlation analysis in patients with or without recurrent mitral regurgitation in the medium term. RESULTS: Medium-term survival was 91.9% and freedom from moderate or severe mitral regurgitation was 89.6%. In medium-term follow-up, transthoracic echocardiography found a significant decrease in tethering area, coaptation height, and distance between the commissures compared to the pre-surgery values (p = 0.0001 in all). The distance between the papillary muscles was reduced compared to the pre-surgery period but it was not significant (p = 0.204). Pearson correlation analysis found no significant correlation between the tethering area and left ventricle sphericity in patients without recurrent mitral regurgitation (r = 0.15, p = 0.36), a highly positive correlation (r = 0.44, p < 0.001) in patients with mild recurrent mitral regurgitation, and a moderately positive correlation (r = 0.71, p < 0.01) in patients with moderate or severe recurrent mitral regurgitation. CONCLUSIONS: The tethering area, coaptation height, and distance between the commissures decreased significantly, thus posterior leaflet segment 2 plication in addition to ring annuloplasty may be the optional procedure to ensure freedom from moderate or severe mitral regurgitation.
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Ay et al. (2014) conducted a cohort in functional ischemic mitral regurgitation (n=136). Plication of posterior leaflet segment 2 in addition to ring annuloplasty was evaluated on Medium-term survival. Plication of posterior leaflet segment 2 in addition to ring annuloplasty resulted in 91.9% medium-term survival and 89.6% freedom from moderate or severe mitral regurgitation.
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