Key result
Following surgical annuloplasty for ischemic mitral regurgitation, augmented posterior mitral leaflet tethering was the primary determinant of postoperative coaptation length (r2=0.60, P<0.0001).
Why the study?
What are the echocardiographic mechanisms of persistent ischemic mitral regurgitation after surgical annuloplasty?
Population
31 patients with surgical annuloplasty for ischemic mitral regurgitation (MR) and 20 controls
Comparison
Surgical annuloplasty vs Controls and internal comparison between…
Design
Cohort
Follow-up
early after surgery
Authors
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Augmented posterior leaflet tethering may explain persistent IMR post-annuloplasty; extends mechanistic insight but leaves open therapeutic implications.
Observational (n=51)
What are the echocardiographic mechanisms of persistent ischemic mitral regurgitation after surgical annuloplasty?
Effect estimate: r2=0.60
p-value: p=<0.0001
Persistent ischemic mitral regurgitation after surgical annuloplasty is primarily driven by augmented posterior mitral leaflet tethering.
Zhu et al. (2005) conducted an observational in Ischemic mitral regurgitation (n=51). Surgical annuloplasty vs. Controls / Patients without persistent MR was evaluated on Determinants of postoperative coaptation length (r2=0.60, p=<0.0001). Following surgical annuloplasty for ischemic mitral regurgitation, augmented posterior mitral leaflet tethering was the primary determinant of postoperative coaptation length (r2=0.60, P<0.0001).
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