Key result
Augmented and progressive posterior mitral leaflet tethering was the primary determinant of recurrent or persistent ischemic mitral regurgitation late after surgical annuloplasty (r2=0.75, P<0.0001).
Why the study?
What are the echocardiographic determinants of recurrent/persistent ischemic/functional mitral regurgitation late after surgical annuloplasty?
Population
30 patients with surgical annuloplasty for ischemic mitral regurgitation and 20 controls
Comparison
Surgical annuloplasty vs Controls and internal comparison between…
Design
Cohort
Authors
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Tethering assessment may refine annuloplasty candidacy; leaves open whether tethering-targeted strategies improve durability.
Observational (n=50)
What are the echocardiographic determinants of recurrent/persistent ischemic/functional mitral regurgitation late after surgical annuloplasty?
Effect estimate: r2=0.75
p-value: p=<0.0001
Recurrent or persistent ischemic mitral regurgitation late after surgical annuloplasty is primarily driven by augmented and progressive posterior mitral leaflet tethering.
Kuwahara et al. (2006) conducted an observational in Ischemic/functional mitral regurgitation (n=50). Surgical annuloplasty vs. Controls (and patients without late MR) was evaluated on Primary determinant of late recurrent/persistent mitral regurgitation (r2=0.75, p=<0.0001). Augmented and progressive posterior mitral leaflet tethering was the primary determinant of recurrent or persistent ischemic mitral regurgitation late after surgical annuloplasty (r2=0.75, P<0.0001).
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