Key result
A 34-year-old man with von Hippel-Lindau disease developed fatal neurogenic pulmonary edema 36 hours after surgical excision of a posterior fossa hemangioblastoma, with autopsy revealing intense focal dorsal medullary edema.
Case Report (n=1)
This case report provides rare human evidence correlating specific brain-stem lesions, specifically dorsal medullary edema, with the pathogenesis of neurogenic pulmonary edema.
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Raises possibility of dorsal medullary involvement in fatal neurogenic pulmonary edema; hypothesis-generating and leaves mechanistic confirmation open.
Brown et al. (1986) conducted a case report in Neurogenic pulmonary edema, von Hippel-Lindau disease, cerebellar hemangioblastoma (n=1). Surgical excision of posterior fossa hemangioblastoma was evaluated on Development of neurogenic pulmonary edema and death. A 34-year-old man with von Hippel-Lindau disease developed fatal neurogenic pulmonary edema 36 hours after surgical excision of a posterior fossa hemangioblastoma, with autopsy revealing intense focal dorsal medullary edema.
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