Key result
In patients treated with orbital atherectomy for severely calcified coronary lesions, in-hospital and 30-day MACE rates did not differ between females (n=157) and males (n=286).
Why the study?
Does gender affect acute and 30-day clinical outcomes in patients undergoing orbital atherectomy for severely calcified coronary lesions?
Population
443 subjects with de novo, severely calcified coronary lesions enrolled in the US-based ORBIT II trial.
Comparison
Orbital atherectomy to facilitate stent delivery vs Male vs female gender
Design
Cohort, nonrandomized
Follow-up
30 days
Authors
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Similar outcomes by gender observed; leaves open whether orbital atherectomy mitigates prior PCI gender disparities in calcified lesions.
Observational (n=443)
Yes
Does gender affect acute and 30-day clinical outcomes in patients undergoing orbital atherectomy for severely calcified coronary lesions?
Orbital atherectomy for severely calcified coronary lesions yields similar acute and 30-day safety and efficacy outcomes in both men and women, despite women having higher baseline clinical risk.
Kim et al. (2015) conducted an observational in de novo, severely calcified coronary lesions (n=443). Female gender vs. Male gender was evaluated on Major adverse cardiac events (MACE) in-hospital and 30-days postprocedure. In patients treated with orbital atherectomy for severely calcified coronary lesions, in-hospital and 30-day MACE rates did not differ between females (n=157) and males (n=286).
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