Key result
Lower body negative pressure significantly reduced the initial rapid increase in forearm vascular conductance during handgrip exercise compared to control (101.6 vs 126.6 ml.min-1.100 mmHg-1; P=0.003).
Why the study?
Does lower body negative pressure alter forearm vascular conductance at the onset of exercise in healthy subjects?
Population
9 healthy subjects
Comparison
5 min of moderate dynamic forearm handgrip… vs 5 min of moderate dynamic forearm handgrip…
Authors
Loading...
Attenuates exercise hyperemia under orthostatic stress; leaves open relevance to clinical populations with autonomic impairment.
Does lower body negative pressure alter forearm vascular conductance at the onset of exercise in healthy subjects?
Absolute Event Rate: 101.6% vs 126.6%
p-value: p=0.003
Local substances released at the onset of muscle contractions rapidly impair sympathetic neural vasoconstrictor effectiveness, demonstrating functional sympatholysis.
Tschakovsky et al. (2003) studied Healthy (n=9). Lower body negative pressure (LBNP) vs. Without LBNP (control) was evaluated on Forearm vascular conductance (FVC) plateau between 10 and 20 s of exercise onset (p=0.003). Lower body negative pressure significantly reduced the initial rapid increase in forearm vascular conductance during handgrip exercise compared to control (101.6 vs 126.6 ml.min-1.100 mmHg-1; P=0.003).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: