Key result
Severe LV dysfunction (LVEF <30%) independently predicted arrhythmia recurrence after catheter ablation for post-infarction VT compared to LVEF 41-51% (HR 2.16; 95% CI 1.15-4.06; p=0.02).
Why the study?
Severe LV dysfunction and advanced age are associated with VT recurrence after catheter ablation in post-infarction drug-refractory VT, prompting analysis of long-term outcomes after single and repeat ablation.
Population
144 patients with post-infarction recurrent VT undergoing catheter ablation
Comparison
Subgroups based on LVEF (<30% vs 30-40% vs 41-51%) and single vs repeat ablation
Design
Retrospective cohort study
Follow-up
Median 46 [17-78] months
Authors
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May stratify post-MI VT ablation risk; hypothesis-generating and requires prospective validation before guiding practice.
Cohort (n=144)
No
Hazard Ratio: 2.16 (95% CI 1.15–4.06)
p-value: p=.02
In patients with post-infarction recurrent ventricular tachycardia, severe left ventricular dysfunction (LVEF <30%) is a strong independent predictor of arrhythmia recurrence following catheter ablation.
Haanschoten et al. (2019) conducted a cohort in post-infarction recurrent ventricular tachycardia (n=144). Severe LV dysfunction (LVEF < 30%) vs. Mild LV dysfunction (LVEF 41-51%) was evaluated on arrhythmia recurrence (HR 2.16, 95% CI 1.15-4.06, p=.02). Severe LV dysfunction (LVEF <30%) independently predicted arrhythmia recurrence after catheter ablation for post-infarction VT compared to LVEF 41-51% (HR 2.16; 95% CI 1.15-4.06; p=0.02).
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