What question did this study set out to answer?

The study aims to assess the status of home blood pressure in a Japanese urban population, comparing normotensive and hypertensive groups.

January 1, 2005Hypertension ResearchOpen Access

Status of Home Blood Pressure Measured in Morning and Evening: Evaluation in Normotensives and Hypertensives in Japanese Urban Population

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Hypertension (n=700). Intervention: Morning-only antihypertensive medication administration vs. Other administration schedules. Primary outcome: Morning home diastolic blood pressure (MD 6 mmHg, p=0.005).

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Key result

In treated hypertensive patients, taking antihypertensive medication only in the morning was associated with a 6 mmHg higher morning home diastolic blood pressure (p=0.005) compared to other administration schedules.

Why the study?

Does home blood pressure measurement identify masked hypertension and poorly controlled morning blood pressure compared to casual blood pressure in an urban Japanese population?

Population

700 adult volunteers recruited from a company in Tokyo, Japan, including normotensive subjects, nontreated…

Comparison

Home blood pressure measurement. vs Casual (clinic) blood pressure measurement.

Design

Cross-sectional

Follow-up

7 days

Authors

HKHiroshi KawabeNational Defence Academy ISIkuo SaitoHiroshima University TSTakao SarutaNorthwestern University

Discussion

Member takes

Implication

Home BP values differ from casual readings across groups; leaves open standardization of home monitoring thresholds in Japanese cohorts.

Key Points

The study aims to assess the status of home blood pressure in a Japanese urban population, comparing normotensive and hypertensive groups.
Analyzed home blood pressure in 468 males and 232 females, mean age 41, recruited from a Tokyo company.
Measuring devices used: Omron HEM-759P with triplicate morning and evening measurements over 7 days.
Comparison of casual and home blood pressure across normotensives and hypertensives, with 70 treated hypertensive patients included.
In the treated hypertensive group, morning blood pressure was significantly higher than evening BP; morning SBP was 139 mmHg and evening SBP was 130 mmHg.
7.2% of normotensive subjects were classified as hypertensive by home blood pressure.
Treated hypertension control was inadequate, particularly in those taking medication only in the morning.

Study Design

Type

Cross-Sectional (n=700)

Multicenter

Structured PICO

Does home blood pressure measurement identify masked hypertension and poorly controlled morning blood pressure compared to casual blood pressure in an urban Japanese population?

Population

700 adult volunteers (mean age 41 years, 33.1% female) from a company in Tokyo, including normotensive and hypertensive subjects, who measured home blood pressure for 7 consecutive days.

Exposure

Home blood pressure measurement (triplicate morning and evening measurements on 7 consecutive days using a semi-automatic device).

Comparator

Casual (clinic) blood pressure measurement.

Outcome

Proportion of subjects classified as hypertensive by home blood pressure (≥135/85 mmHg) despite being normotensive or controlled by casual blood pressure (<140/90 mmHg).surrogate

Main Result

Mean Difference: 6

p-value: p=0.005

Home blood pressure monitoring identifies a significant proportion of masked hypertension in normotensives and poorly controlled morning blood pressure in treated hypertensives that is missed by casual clinic measurements.

Limitations

Casual blood pressure was based on only one value measured within 1 month before or after home measurement, potentially including white-coat hypertensives.
Home blood pressure values may have been underestimated because the higher first measurement value was discarded.
The number of treated hypertensive patients was small (n=70).
Casual blood pressure was measured only once within 1 month before or after home blood pressure measurement, potentially introducing a white-coat effect.
The first home blood pressure value was discarded, which may have led to underestimation of home blood pressure.
The number of treated hypertensive patients was small.

Cite This Study

Kawabe et al. (2005) conducted a cross-sectional in Hypertension (n=700). Morning-only antihypertensive medication administration vs. Other administration schedules was evaluated on Morning home diastolic blood pressure (MD 6 mmHg, p=0.005). In treated hypertensive patients, taking antihypertensive medication only in the morning was associated with a 6 mmHg higher morning home diastolic blood pressure (p=0.005) compared to other administration schedules.

synapsesocial.com/papers/6a6e58edf44fa9f079dc1f24 https://doi.org/10.1291/hypres.28.491

Topics

Hypertension management

View Full Paper

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January 1, 2005Hypertension ResearchOpen Access

Status of Home Blood Pressure Measured in Morning and Evening: Evaluation in Normotensives and Hypertensives in Japanese Urban Population

View Full Paper

Ask AI

Bookmark

Key result

Why the study?

Does home blood pressure measurement identify masked hypertension and poorly controlled morning blood pressure compared to casual blood pressure in an urban Japanese population?

Population

700 adult volunteers recruited from a company in Tokyo, Japan, including normotensive subjects, nontreated…

Comparison

Home blood pressure measurement. vs Casual (clinic) blood pressure measurement.

Design

Cross-sectional

Follow-up

7 days

Authors

HKHiroshi KawabeNational Defence Academy ISIkuo SaitoHiroshima University TSTakao SarutaNorthwestern University

Discussion

Member takes

Implication

Home BP values differ from casual readings across groups; leaves open standardization of home monitoring thresholds in Japanese cohorts.

Key Points

The study aims to assess the status of home blood pressure in a Japanese urban population, comparing normotensive and hypertensive groups.
Analyzed home blood pressure in 468 males and 232 females, mean age 41, recruited from a Tokyo company.
Measuring devices used: Omron HEM-759P with triplicate morning and evening measurements over 7 days.
Comparison of casual and home blood pressure across normotensives and hypertensives, with 70 treated hypertensive patients included.
In the treated hypertensive group, morning blood pressure was significantly higher than evening BP; morning SBP was 139 mmHg and evening SBP was 130 mmHg.
7.2% of normotensive subjects were classified as hypertensive by home blood pressure.
Treated hypertension control was inadequate, particularly in those taking medication only in the morning.

Study Design

Type

Cross-Sectional (n=700)

Multicenter

Structured PICO

Does home blood pressure measurement identify masked hypertension and poorly controlled morning blood pressure compared to casual blood pressure in an urban Japanese population?

Population

700 adult volunteers (mean age 41 years, 33.1% female) from a company in Tokyo, including normotensive and hypertensive subjects, who measured home blood pressure for 7 consecutive days.

Exposure

Home blood pressure measurement (triplicate morning and evening measurements on 7 consecutive days using a semi-automatic device).

Comparator

Casual (clinic) blood pressure measurement.

Outcome

Proportion of subjects classified as hypertensive by home blood pressure (≥135/85 mmHg) despite being normotensive or controlled by casual blood pressure (<140/90 mmHg).surrogate

Main Result

Mean Difference: 6

p-value: p=0.005

Limitations

Casual blood pressure was based on only one value measured within 1 month before or after home measurement, potentially including white-coat hypertensives.
Home blood pressure values may have been underestimated because the higher first measurement value was discarded.
The number of treated hypertensive patients was small (n=70).
Casual blood pressure was measured only once within 1 month before or after home blood pressure measurement, potentially introducing a white-coat effect.
The first home blood pressure value was discarded, which may have led to underestimation of home blood pressure.
The number of treated hypertensive patients was small.

Cite This Study

synapsesocial.com/papers/6a6e58edf44fa9f079dc1f24 https://doi.org/10.1291/hypres.28.491

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Topics

Hypertension management

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