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May 21, 2025Journal of Pure and Applied MicrobiologyOpen Access

Common Genotypes of Carbapenamase Observed in Members of the Enterobacteriaceae in Tertiary Care Hospital in South India

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Authors

BAB AppalarajuPSG Institute of Medical Sciences & ResearchMRM. Mohamadiya RizwanaPSG Institute of Medical Sciences & ResearchSSS ShanmugapriyaMadurai Medical College

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Overview

Retrospective investigation estimates carbapenem-producing genes in Enterobacteriaceae, suggesting potential treatment improvements.

Key Points

  • Estimate the prevalence of genes linked to carbapenemase production in Enterobacteriaceae.
  • Retrospective analysis of isolates from various samples including blood and respiratory fluids.
  • Used Carba-R testing with GENE Xpert Carba-R Assay for detection of carbapenemase genes.
  • Data collected from specimens between January 2020 and August 2023.
  • 10.6% of Enterobacteriaceae were carbapenem-resistant.
  • OXA-48 genotype was most prevalent in 31%, followed by NDM (25%) and KPC (1.3%).
  • 37% of isolates exhibited both OXA-48 and NDM genes.

Cite This Study

Appalaraju et al. (2025) studied this question.

synapsesocial.com/papers/6a6e64af26770c2b8ddfc0e5https://doi.org/10.22207/jpam.19.2.15
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