What is the clinical evidence from this study?

Study design: Observational. Population: Acute non-bacterial gastroenteritis (n=831). Intervention: Human rotavirus (HRV) serotypes. Primary outcome: Prevalence of the 4 established human rotavirus (HRV) serotypes.

What question did this study set out to answer?

The study aims to evaluate the prevalence of human rotavirus serotypes in European countries from 1981 to 1988.

January 1, 1990Scandinavian Journal of Infectious Diseases

Prevalence of Human Rotavirus Serotypes in Some European Countries 1981–1988

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Key result

Serotype 1 human rotavirus strains were largely predominant among 831 fecal strains from European infants and young children with acute non-bacterial gastroenteritis during 1981-1988.

Key Points

The study aims to evaluate the prevalence of human rotavirus serotypes in European countries from 1981 to 1988.
Analyzed 831 fecal strains from infants and young children with acute gastroenteritis.
Used enzyme-linked immunosorbent assay and immune electron microscopy for typing.
Identified serotypes based on VP7 type-specific monoclonal antibodies.
Serotype 1 HRV strains predominated during this period, particularly in Italy.
Serotype 4 strains were less common, and both serotypes were equivalent only in 1983-84.
Serotypes 2 and 3 were infrequently found, with only 8 strains of serotype 3 identified, and approximately 10% of strains could not be typed.

Study Design

Type

Observational (n=831)

Multicenter

Yes

Structured PICO

Population

831 fecal strains collected from infants and young children with acute non-bacterial gastroenteritis in Europe between 1981 and 1988.

Outcome

Prevalence of the 4 established human rotavirus (HRV) serotypes

Serotype 1 was the predominant human rotavirus strain in Europe from 1981-1988, providing important epidemiological data for regional vaccine development strategies.

Discussion

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Implication

Historical European surveillance data establish serotype 1 baseline; leaves open current distribution after rotavirus vaccination.

Cite This Study

Gerna et al. (1990) conducted an observational in Acute non-bacterial gastroenteritis (n=831). Human rotavirus (HRV) serotypes was evaluated on Prevalence of the 4 established human rotavirus (HRV) serotypes. Serotype 1 human rotavirus strains were largely predominant among 831 fecal strains from European infants and young children with acute non-bacterial gastroenteritis during 1981-1988.

synapsesocial.com/papers/6a6e876ba528af2d65c2c327 https://doi.org/10.3109/00365549009023112

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Prevalence of Human Rotavirus Serotypes in Some European Countries 1981–1988

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Prevalence of Human Rotavirus Serotypes in Some European Countries 1981–1988

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider