Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
July 14, 2026Frontiers in MedicineOpen Access

Risk factors for hospital readmission in chronic obstructive pulmonary disease: a systematic review and meta-analysis

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Evaluating readmission rates at different follow-up time points and identifying factors associated with COPD-related readmission are important for risk assessment, early recognition of high-risk patients, and targeted interventions.

Population

Patients with COPD across 54 observational studies

Comparison

Factors associated with COPD-related readmission

Design

Systematic review and meta-analysis of observational studies

Follow-up

Within 1 month, 3 months, 6 months, and 1 year

Key result

Among patients hospitalized for chronic obstructive pulmonary disease, the pooled readmission rate was 15.2% at 1 month and increased progressively to 42.1% at 1 year.

Authors

HTHao TianWSWei ShenLHLiuyang Huang

Discussion

Loading...

Member takes

Overview

Reinforces post-discharge COPD attention in practice; extends observational evidence but leaves causal intervention effects open.

Study Design

Type

Systematic Review (n=31,161,712)

Structured PICO

P
Population
31,161,712 patients with chronic obstructive pulmonary disease from 54 observational studies, evaluated for readmission rates and associated risk factors up to 1 year post-discharge.
O
Outcome
COPD-related readmission rates within 1 month, 3 months, 6 months, and 1 year after hospital discharge, and factors associated with COPD-related readmissionhard clinical

COPD-related hospital readmission is highly prevalent, reaching 42.1% at 1 year, and is driven by multiple identifiable clinical factors, highlighting the need for targeted post-discharge interventions.

Limitations

  • Substantial heterogeneity was observed in several pooled analyses.
  • Differences in study populations, healthcare systems, COPD severity, follow-up duration, readmission definitions, and covariate adjustment across studies.
  • Several pooled estimates retained wide confidence intervals and substantial heterogeneity.
  • Substantial clinical and methodological heterogeneity across included studies
  • Potential publication bias for 1-month readmission rates
  • Only three studies reported 6-month readmission rates

Cite This Study

Tian et al. (2026) conducted a systematic review in Chronic obstructive pulmonary disease (COPD) (n=31,161,712). Hospital discharge for COPD was evaluated on 1-year COPD-related readmission rate (95% CI 33.60-51.10). Among patients hospitalized for chronic obstructive pulmonary disease, the pooled readmission rate was 15.2% at 1 month and increased progressively to 42.1% at 1 year.

synapsesocial.com/papers/6a6ea455f44fa9f079dc444ehttps://doi.org/10.3389/fmed.2026.1836031
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Readmission rate for acute exacerbation of chronic obstructive pulmonary disease: A systematic review and meta-analysis2022 · 80 citations
  2. 2All-cause readmission rate and risk factors of 30- and 90-day after discharge in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis2023 · 17 citations
  3. 3Risk assessment of readmissions following an initial COPD-related hospitalization2013 · 96 citations
  4. 4Risk factors for early readmission after acute exacerbation of chronic obstructive pulmonary disease2020 · 18 citations
  5. 5Predictors of Early Readmission among Patients 40 to 64 Years of Age Hospitalized for Chronic Obstructive Pulmonary Disease2014 · 137 citations