Influencing factors of esophageal pH in patients with reflux esophagitis

Objective To explore the influencing factors of esophageal pH in patients with reflux esophagitis (RE). Methods Thirty-five patients with RE who had normal esophageal pH value in General Hospital of Jinmei Group from June 2017 to June 2018 were selected as the observation group. Another 40 patients with abnormal esophageal pH value were selected as the control group. The cause of abnormal esophageal pH in some patients with RE was analyzed. Results There was no significant difference in RE classification in the observation group (P>0.05). There was no significant difference in the Helicobacter pylori infection rate between the two groups (P>0.05). The incidence of combined and hiatal hernia was 0.00%, the incidence of combined and hiatal hernia was 20.00%, and the difference between the groups was significant (P 0.05), but there was no significant difference in LESR (P>0.05). The anal side peristalsis of the esophageal body in the observation group was significantly higher than that of the control group, and the difference between the groups was significant (P 0.05). Conclusions Helicobacter pylori infection has no significant effect on the esophageal pH of patients with RE, and strong barrier function and clearance function may be important factors affecting the normal pH value of RE patients.