The effects of NLRP3 rs10754558 and rs4612666 polymorphisms on preeclampsia susceptibility, onset, and severity: a case-control study and in silico analysis.

Figures

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  Figure 1. In silico prediction of splice motifs for wild-type and mutated type of NLRP3 rs10754558 and rs4612666 polymorphisms using SpliceAid 2. The width of the bars depends on the number of nucleotides in the binding region and the height of the bars depends on its affinity (score).

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  Figure 2. The secondary structure change in RNA due to nucleotide substitution by RNAsnp tool