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August 2, 2026Journal of materials research/Pratt's guide to venture capital sourcesOpen Access

Evaluation of the physicochemical and biological properties of calcium silicate-based sealers with different plasticizing agents

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Authors

TAThiago Bessa Marconato AntunesGCGabriel Bispo CarvalhoCSCamila S. Stolf

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Overview

Randomized trial evaluates physicochemical and biological properties of calcium silicate sealers, suggesting improved handling with polymer additives.

Key Points

  • The aim is to assess how various plasticizers affect the physicochemical and biological properties of calcium silicate-based sealers.
  • Comparative analysis of different sealers containing various plasticizers.
  • Evaluation of physicochemical properties according to ISO 6876:2012 guidelines.
  • Assessment of antimicrobial activity and cytocompatibility of sealers.
  • PVA-containing sealer showed the lowest solubility at 0.21% and highest cell viability (p < 0.05).
  • Cellulose-based plasticizers negatively impacted the flowability of sealers.
  • No antimicrobial activity was observed in any formulations.

Cite This Study

Antunes et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeaa21b0468a7eeab2e4ehttps://doi.org/10.1557/s43578-026-01917-3
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