What question did this study set out to answer?

To evaluate the links between post-transplant immune reconstitution and viral reactivation in patients after allogeneic HSCT.

August 2, 2026HematologyOpen Access

Immune reconstitution and viral reactivation after allogeneic hematopoietic stem cell transplantation in hematologic malignancies

View Full Paper

Ask AI

Bookmark

To evaluate the links between post-transplant immune reconstitution and viral reactivation in patients after allogeneic HSCT.
Retrospective observational cohort study of 312 patients with hematologic malignancies who underwent HSCT.
Longitudinal assessment of bone marrow B-cell and peripheral blood lymphocyte subsets via flow cytometry.
Logistic regression and Cox regression used to analyze associations and overall survival determinants.
CMV and EBV DNAemia/reactivation occurred in 42.0% and 31.4% of patients, respectively; significant correlation found (ρ = 0.191, p = 0.028).
Higher bone marrow B-cell proportion at six months correlated with lower odds of CMV reactivation (OR = 0.947, 95% CI: 0.901–0.995, p = 0.034).
Overall survival was primarily linked to relapse (HR = 5.5, p < 0.001), while viral reactivation showed no significant association.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Retrospective cohort study evaluates immune recovery and viral reactivation effects on survival in hematologic malignancies, indicating important associations.

Cite This Study

Qaiser et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeabf1b0468a7eeab3362 https://doi.org/10.1080/16078454.2026.2707676

View Full Paper

Ask AI

Bookmark

Implication

Retrospective cohort study evaluates immune recovery and viral reactivation effects on survival in hematologic malignancies, indicating important associations.

Immune reconstitution and viral reactivation after allogeneic hematopoietic stem cell transplantation in hematologic malignancies

Key Points

Discussion

Implication

Cite This Study

Immune reconstitution and viral reactivation after allogeneic hematopoietic stem cell transplantation in hematologic malignancies

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider