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August 2, 2026DiseasesOpen Access

Thiamine Deficiency in Hospitalized Veterans Without Alcohol Use Disorder: Prevalence, Biomarker Assessment, and Clinical Characteristics

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Authors

EMElisabeth MatesAKAlexandrea Kilgore-GomezCPClaire Phibbs

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Overview

Randomized trial evaluates thiamine deficiency prevalence in veterans, highlighting the need for biomarker confirmation.

Key Points

  • The study aims to assess the prevalence of thiamine deficiency in hospitalized veterans without alcohol use disorder and describe the clinical characteristics of related disorders.
  • Recruited newly hospitalized veterans without alcohol use disorder.
  • Collected fasting plasma and whole-blood thiamine samples, along with clinical assessments.
  • Participants were invited for reexamination after thiamine repletion to note symptom changes.
  • 26.44% of participants had low plasma thiamine; 97.92% of these showed clinical signs of thiamine deficiency disorders.
  • Cognitive scores improved significantly (p = 0.0093) and motor strength (p = 0.0417) after repletion.
  • Whole-blood thiamine testing missed a substantial number of cases compared to plasma thiamine.

Cite This Study

Mates et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeae61b0468a7eeab37eahttps://doi.org/10.3390/diseases14080275
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Thiamine and Micronutrient Deficiencies in Hospitalized Veterans Without Alcohol Use Disorder2026 · 1 citations
  2. 2Thiamine deficiency in cancer patients at initial admission to a palliative care unit: a single-centre cross-sectional study2026
  3. 3Whole Blood Thiamine Levels in Extreme Anorexia Nervosa: A Pilot Study2025
  4. 4A study on serum thiamine in patients of alcohol dependence syndrome at a tertiary care hospital2025
  5. 5Subclinical thiamine deficiency in third-trimester pregnancy despite routine antenatal supplementation: a cross-sectional study in an urban setting, Bangkok, Thailand2026