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August 2, 2026NMO journalOpen Access

Clinical Heterogeneity in Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Case Series

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Authors

PSPihu SethiCSChandan SinghMGMehak Gupta

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Overview

Case series reports diverse aetiologies and highlights the importance of tailored management in epidermal necrolysis.

Key Points

  • This research aims to explore the clinical variations and management strategies in Stevens-Johnson syndrome and toxic epidermal necrolysis.
  • Case series of three patients with clinically varying epidermal necrolysis.
  • Assessment of severity-of-illness scores for prognostic evaluation.
  • Individualized immunomodulatory therapy along with supportive care.
  • All patients experienced clinical improvement after aetiological differentiation.
  • Utilization of severity scores improved prognostic assessment.
  • Tailored management strategies were effective in promoting recovery.

Cite This Study

Sethi et al. (2026) studied this question.

synapsesocial.com/papers/6a6eeaf51b0468a7eeab39cehttps://doi.org/10.4103/jnmo.jnmo_44_26
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Spectrum: A Report of Two Contrasting Cases Managed in a Burn Unit2026
  2. 2Pathogenesis and A Practical Guide to the Management of Steven-Johnson Syndrome & Toxic Epidermal Necrolysis2024
  3. 3Stevens Johnson Syndrome and Toxic Epidermal Necrolysis Updates on Management2024
  4. 4WHEN SKIN TURNS AGAINST THE BODY: A CLOSER LOOK AT SJS AND TEN2025
  5. 5Clinical features of Stevens — Johnson syndrome and toxic epidermal necrolysis: An observational cohort retrospective study2025