Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 15, 1996Circulation

Hibernating Myocardium Has Reduced Blood Flow at Rest That Increases With Low-Dose Dobutamine

View Full Paper
Ask AI
Bookmark
Share

Key result

Low-dose dobutamine improves abnormal left ventricular wall motion in hibernating myocardium, which has reduced resting blood flow, but carries a risk of infarction.

Why the study?

Does low-dose dobutamine affect myocardial blood flow and LV wall motion in patients with hibernating myocardium?

Population

Patients with hibernating myocardium (HM) and coronary artery disease

Design

Editorial

Authors

SRShahbudin H. RahimtoolaStructural Heart Disease

Discussion

Loading...

Member takes

Implication

Clinical caution warranted with low-dose dobutamine due to infarction risk; Level 5 evidence leaves optimal use open.

Structured PICO

Does low-dose dobutamine affect myocardial blood flow and LV wall motion in patients with hibernating myocardium?

P
Population
Patients with hibernating myocardium (HM) and coronary artery disease
I
Intervention
Low-dose dobutamine
O
Outcome
Myocardial blood flow (MBF) and left ventricular (LV) wall motionsurrogate

This editorial highlights that while low-dose dobutamine improves LV wall motion in hibernating myocardium, it carries a risk of infarction and requires caution during use.

Limitations

  • Conclusions about areas of LV dysfunction with 'normal' MBF in coronary artery disease are problematic based on the presented data.
  • Conclusions about areas of LV dysfunction with 'normal' MBF in coronary artery disease are problematic

Cite This Study

Shahbudin H. Rahimtoola (1996) conducted an editorial in Hibernating Myocardium. Low-Dose Dobutamine was evaluated. Low-dose dobutamine improves abnormal left ventricular wall motion in hibernating myocardium, which has reduced resting blood flow, but carries a risk of infarction.

synapsesocial.com/papers/6a6eeb2afebe604dd708145dhttps://doi.org/10.1161/01.cir.94.12.3055

Topics

Echocardiography
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of dobutamine on regional myocardial blood flow and ventricular performance during acute and chronic myocardial ischemia in dogs.1976 · 105 citations
  2. 2Adaptive responses of coronary circulation and myocardium to chronic reduction in perfusion pressure and flow1994 · 109 citations
  3. 3Low-dose dobutamine echocardiography detects reversible dysfunction after thrombolytic therapy of acute myocardial infarction.1993 · 403 citations