Key result
Surgical excision of a recurrent 15mm cellular fibrous histiocytoma on the right fourth toe confirmed the diagnosis with no complications.
Why the study?
Cellular fibrous histiocytoma has a high recurrence rate and is frequently misdiagnosed due to morphological similarities with sarcomas, with no previously reported occurrence on the foot.
Case Report (n=1)
This case highlights the first reported occurrence of a cellular fibrous histiocytoma on the foot and emphasizes the importance of accurate histopathological diagnosis to avoid misdiagnosis.
A cellular fibrous histiocytoma (CFH) is a variant of fibrous histiocytomas with increased cellularity with a fascicular growth pattern and increased frequency to extend into the subcutis. CFH is a benign nodular growth with a high recurrence rate of 26%. It is regularly confused with dermatofibrosarcoma protuberans and leiomyosarcoma due to their morphological similarities, hence emphasizing the importance of proper diagnosis. In this article, we discuss the case of a 50-year-old male who presents with a recurrence of CFH 30 years post-excision. The 15mm lesion on the right fourth toe was previously diagnosed and excised as a granuloma, highlighting the error in misdiagnosis. In regard to the current case, a surgical excision was performed, and histopathology testing confirmed the diagnosis of CFH with no complication. To this date, there is no occurrence of a CFH on the foot reported in the literature.
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Parihar et al. (2022) conducted a case report in Cellular fibrous histiocytoma (n=1). Surgical excision was evaluated. Surgical excision of a recurrent 15mm cellular fibrous histiocytoma on the right fourth toe confirmed the diagnosis with no complications.
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