Key result
Elongation factor G releases ribosome recycling factor from 70 S ribosomal and model post-termination complexes, a process stimulated by GTP analogues and required for complex disassembly.
Population
70 S ribosomal and model post-termination complexes, and 50 S ribosomal subunit complexes
Design
Preclinical
Authors
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EF-G selectively releases RRF from 70S complexes; extends ribosome recycling models but leaves open in vivo and therapeutic relevance.
The release of ribosome-bound RRF by EF-G is required for post-termination complex disassembly, involving a positional change of RRF on the ribosome.
Kiel et al. (2003) studied this question. Elongation factor G (EF-G) was evaluated on Release of RRF from 70 S ribosomal and model post-termination complexes. Elongation factor G releases ribosome recycling factor from 70 S ribosomal and model post-termination complexes, a process stimulated by GTP analogues and required for complex disassembly.
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