Key result
A longer average daily rehabilitation time significantly reduced the odds of instrumental activity of daily living decline during hospitalization compared to a shorter rehabilitation time in older patients with heart failure (OR 0.475).
Why the study?
Limitation of instrumental activity of daily living is independently associated with adverse prognosis in older heart failure patients, but the relationship between average daily rehabilitation time and risk of IADL decline during acute hospitalization was unknown.
Does longer average daily rehabilitation time prevent IADL decline in older patients hospitalized for acute heart failure?
Cohort (n=411)
Yes
Does longer average daily rehabilitation time prevent IADL decline in older patients hospitalized for acute heart failure?
Odds Ratio: 0.475 (95% CI 0.231–0.975)
Absolute Event Rate: 14% vs 33%
p-value: p=0.042
Longer average daily rehabilitation time during acute hospitalization for heart failure is associated with a reduced risk of decline in instrumental activities of daily living.
Should not yet change practice in older HF inpatients; leaves open a potential dose-response benefit for IADL preservation.
BACKGROUND: Limitation of instrumental activity of daily living (IADL) is independently associated with an adverse prognosis in older heart failure (HF) patients. AIMS: This multicenter study aims to examine the relationship between average daily rehabilitation time (ADRT) and risk of IADL decline during acute hospitalization in older patients with HF. METHODS: Four hundred eleven older patients who were hospitalized due to acute HF and underwent rehabilitation were divided into three groups based on the tertile of the ADRT: short, intermediate, and long groups. IADL was assessed by the National Center for Geriatrics and Gerontology Activities of Daily Living (NCGG-ADL) scale. Change in NCGG-ADL (Δ NCGG-ADL) was calculated by subtracting the pre-hospitalization score from the at-discharge score and IADL decline was defined as Δ NCGG-ADL < = -1 point. Logistic regression analysis was carried out examining the association between ADRT and occurrence of IADL decline. RESULTS: The ADRT was 23.9, 32.0, and 38.6 minutes in short, intermediate, and long group, respectively. The proportion of patients with IADL decline during hospitalization was 21% among all subjects and short group had the highest proportion of IADL decline (33%) and long group had the lowest proportion (14%). The long group had significantly lower odds of IADL decline compared with the short group (OR:0.475, 95% CI:0.231-0.975, P = 0.042). Among the items of NCGG-ADL scale, significant decreases in the "go out by oneself", "travel using a bus or train", "shop for necessities", "vacuum", and "manage medication" were observed at discharge compared to pre-hospitalization in the short group (p<0.01, p<0.01, p<0.01, p<0.05, and p<0.05). CONCLUSIONS: The present study demonstrated that short of ADRT may be associated with the risk of IADL decline during hospitalization in older patients with HF.
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Kato et al. (2021) conducted a cohort in Acute heart failure (n=411). Long average daily rehabilitation time vs. Short average daily rehabilitation time was evaluated on Decline in instrumental activity of daily living (IADL) during hospitalization (OR 0.475, 95% CI 0.231-0.975, p=0.042). A longer average daily rehabilitation time significantly reduced the odds of instrumental activity of daily living decline during hospitalization compared to a shorter rehabilitation time in older patients with heart failure (OR 0.475).
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