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October 1, 2019Isokinetics and Exercise Science

The effects of whole body vibration training combined with blood flow restriction on von Willebrand factor response

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Key result

Whole body vibration with blood flow restriction acutely increased von Willebrand factor levels by 17.2% more than WBV alone (p<0.05), but both groups showed equal decrements after 8 weeks.

Why the study?

Blood flow restriction exercise improves muscle performance, but there is limited research on vascular dysfunction, particularly when combining an involuntary muscle contraction modality with blood flow restriction.

Does whole body vibration combined with blood flow restriction affect von Willebrand factor levels in physically inactive men compared to whole body vibration alone?

Comparison

Whole body vibration with blood flow restriction vs whole body vibration alone

Design

Randomized trial

Follow-up

8 weeks

Authors

TLT. M. LinZCZong‐Yan Cai

Discussion

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Overview

Warrants caution with acute BFR addition to WBV; confirms equivalent chronic vascular benefits with or without BFR in inactive men.

Study Design

Type

RCT (n=16)

Structured PICO

Does whole body vibration combined with blood flow restriction affect von Willebrand factor levels in physically inactive men compared to whole body vibration alone?

P
Population
16 physically inactive men randomized to whole body vibration with or without blood flow restriction for 8 weeks.
I
Intervention
Whole body vibration (WBV) combined with blood flow restriction (BFR) via inflatable cuffs on proximal thighs, 10 sets of intermittent WBV exercise 20 min/day, 3 days/week for 8 weeks
C
Comparator
Whole body vibration (WBV) alone, 10 sets of intermittent WBV exercise 20 min/day, 3 days/week for 8 weeks
O
Outcome
von Willebrand factor (vWF) levels (acute and accumulative effects after 8 weeks)surrogate

Main Result

Effect estimate: 17.2% higher increase

p-value: p=< 0.05

While adding blood flow restriction to whole body vibration acutely increases markers of vascular dysfunction, 8 weeks of training with or without blood flow restriction yields similar improvements in vascular function in inactive men.

Cite This Study

Lin et al. (2019) conducted an RCT in Physically inactive (n=16). Whole body vibration (WBV) with blood flow restriction (BFR) vs. Whole body vibration (WBV) alone was evaluated on von Willebrand factor (vWF) levels (17.2% higher increase, p=< 0.05). Whole body vibration with blood flow restriction acutely increased von Willebrand factor levels by 17.2% more than WBV alone (p<0.05), but both groups showed equal decrements after 8 weeks.

synapsesocial.com/papers/6a6f13c1fe4101aa97dfaec8https://doi.org/10.3233/ies-192147
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Effects of Whole-Body Vibration Training with Blood Flow Restriction on Lower Extremity Muscle Activity and Hemodynamic Variables2023
  2. 2Effects of whole body vibration training combined with blood flow restriction on muscle adaptation2020 · 13 citations
  3. 3Effects of combining blood flow restriction with whole-body vibration training on muscle strength and hypertrophy: A systematic review and meta-analysis2026
  4. 4Effects of Whole-Body Vibration Combined with Blood Flow Restriction and Systemic Hypoxia on Body Composition and Physical Performance in Overweight University Students2024
  5. 5Small arteries stay stiff for a longer period following vibration exercises in combination with blood flow restriction2018 · 13 citations