Key result
Phylogenetic analysis of EV71 strains from patients hospitalized with HFMD in Vietnam in 2012 revealed that the dominant subgenogroup was C4.
Population
1,917 samples from patients hospitalised with Hand, Foot and Mouth Disease throughout Vietnam, of which 637…
Design
Cross-sectional
Authors
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C4 dominance in Vietnam's 2012 HFMD outbreak supports regional genomic surveillance; leaves open strain-specific impacts on severity and interventions.
Observational (n=1,917)
Yes
The 2012 HFMD outbreak in Vietnam was primarily driven by the EV71 subgenogroup C4, highlighting the influence of regional strain diversity on local outbreaks.
Donato et al. (2016) conducted an observational in Hand, Foot and Mouth Disease (HFMD) (n=1,917). Enterovirus 71 strains was evaluated on EV71 subgenogroup characterization. Phylogenetic analysis of EV71 strains from patients hospitalized with HFMD in Vietnam in 2012 revealed that the dominant subgenogroup was C4.
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