Key result
Elderly populations with a daily vitamin K intake greater than 89.51 mg had a significantly lower prevalence of periodontitis compared to those with lower intake (OR 0.648).
Why the study?
Despite increasing data linking vitamin K intake to periodontitis progression, its association with periodontitis among older American adults remained to be evaluated.
Does higher vitamin K intake reduce the prevalence of periodontitis in American adults aged 60 years and older?
Cross-Sectional (n=2,303)
Does higher vitamin K intake reduce the prevalence of periodontitis in American adults aged 60 years and older?
Higher dietary vitamin K intake is associated with a reduced prevalence of periodontitis in older US adults.
Answers are grounded in this paper and cite their sources.
Vitamin K intake was associated with periodontitis in older adults; leaves open any causal or interventional role pending prospective data.
BACKGROUND: An increasing amount of data has been acquired on the close relationship between Vitamin K intake and the progression of periodontitis. The purpose of this study was to estimate whether Vitamin K intake is associated with periodontitis among older adults in America using information from the National Health and Nutrition Examination Survey (NHANES) database. METHODS: A cross-sectional analysis of data on periodontal indices and vitamin K intake among American adults aged 60 years and older in the 2009-2014 NHANES database was extracted. Periodontitis was defined according to CDC/AAP criteria, classification of periodontitis and severity of periodontitis according to the degree and amount of attachment loss in the interproximal site, and vitamin K intake was categorized using optimal cutoff value. Univariate and multivariate logistic regression analyses were used to investigate the association between vitamin K intake and the risk of periodontitis. RESULTS: Based on the information analysis of 2303 participants who met the inclusion criteria, the risk of periodontitis was lower in the elderly population with higher vitamin K intake. Especially, a statistically significant reduction in the prevalence of periodontitis was observed in elderly populations with vitamin K intake greater than 89.51 mg/d (OR = 0.648,95%Cl = 0.502-0.837, P value = 0.001) compared to those with vitamin K intake less than 89.51 mg/d. Subgroup analyses revealed that this association was more prominent in elderly people aged 60-69 years and 70-79 years, the female/male population, the Non-Hispanic White population, those with a poverty index of 1.3-3.5, education level over high school grad/GED, non-smokers, 1-5 drinks/month, non-alcohol drinkers, overweight, normal blood pressure and without diabetes. CONCLUSION: Our research found a strong relationship between vitamin K intake and periodontitis among elderly people in the United States, suggesting vitamin K intake is a possible risk factor and may be a novel idea for the diagnosis and treatment of periodontitis.
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Zhu et al. (2025) conducted a cross-sectional in Periodontitis (n=2,303). Vitamin K intake ≥ 89.51 mg/d vs. Vitamin K intake < 89.51 mg/d was evaluated on Prevalence of periodontitis (OR 0.648, 95% CI 0.502-0.837, p=0.001). Elderly populations with a daily vitamin K intake greater than 89.51 mg had a significantly lower prevalence of periodontitis compared to those with lower intake (OR 0.648).
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