September 13, 2012International Journal of Stroke
Risk of Cardiovascular Events and Death in the Life after Aneurysmal Subarachnoid Haemorrhage: A Nationwide Study
Key result
Survivors of subarachnoid haemorrhage had an increased risk of vascular death (SMR 3.4; 95% CI 3.1-3.7) and fatal or nonfatal vascular diseases (SIR 2.7; 95% CI 2.6-2.8).
Why the study?
Are survivors of aneurysmal subarachnoid haemorrhage at increased risk of vascular disease and death?
Population
6,999 patients who survived more than three months after admission for subarachnoid haemorrhage between 1997…
Design
Cohort
Follow-up
mean 5.1 years
Authors
Discussion
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Member takes
Implication
Dutch aSAH registry data on vascular risk need external validation; leaves open whether Swedish mortality patterns generalize.
Study Design
Type
Cohort (n=6,999)
Multicenter
Yes
Structured PICO
Are survivors of aneurysmal subarachnoid haemorrhage at increased risk of vascular disease and death?
P
Population
6,999 patients who survived more than three months after admission for subarachnoid haemorrhage, followed for a mean of 5.1 years.
C
Comparator
General population (implied by standardized incidence and mortality ratios)
O
Outcome
Standardized incidence and mortality ratios for fatal or nonfatal vascular diseases, vascular death, and all-cause deathhard clinical
Main Result
Effect estimate: SMR 3.4 (95% CI 3.1-3.7)
Survivors of aneurysmal subarachnoid haemorrhage have a significantly increased long-term risk of vascular diseases and death.
Cite This Study
Nieuwkamp et al. (2012) conducted a cohort in aneurysmal subarachnoid haemorrhage (n=6,999). Subarachnoid haemorrhage vs. General population was evaluated on vascular death (SMR 3.4, 95% CI 3.1-3.7). Survivors of subarachnoid haemorrhage had an increased risk of vascular death (SMR 3.4; 95% CI 3.1-3.7) and fatal or nonfatal vascular diseases (SIR 2.7; 95% CI 2.6-2.8).