Key result
Atherogenic indices indicated a high risk of cardiovascular disease in the majority of apparently healthy women, with cholindex significantly associated with diastolic blood pressure (B = 3.76).
Why the study?
Cardiovascular disease is the main cause of death worldwide and atherogenic dyslipidemia is an established risk factor, prompting the assessment of atherogenic indices and lipid ratios in women.
What is the prevalence of high atherogenic indices and their relationship with blood pressure and age in apparently healthy women aged 30-55 years?
Cross-Sectional (n=150)
No
What is the prevalence of high atherogenic indices and their relationship with blood pressure and age in apparently healthy women aged 30-55 years?
Effect estimate: B = 3.76 (95% CI 2.87-7.24)
p-value: p=0.035
A high proportion of apparently healthy women aged 30-55 years in Iran have elevated atherogenic indices, indicating a potentially unrecognized high risk for cardiovascular disease.
These indices may flag subclinical risk in healthy women; leaves open prospective validation before clinical use.
Background: Cardiovascular disease (CVD) is the main cause of death worldwide and atherogenic dyslipidemia is an established risk factor for CVD. This cross-sectional study aimed to assess the atherogenic indices and lipid ratios, including atherogenic coefficient (AC), atherogenic index of plasma (AIP), cholindex (CI), Castelli risk index-1 (CRI-1), CRI-2, and non-HDL-C, in women living in the Tabriz, Iran during April–May 2017. Material and methods: Anthropometric measurements, fasting serum lipids, and blood pressure of 150 women aged 30–55 years in Tabriz, Iran was evaluated. The atherogenic indices were calculated by the established formulas. Results: The prevalence of high AIP, AC, CI, CRI-1, CRI-2 and non-HDL-C ratios were 64.5%, 36.2%, 20.4%, 77%, 7.2% and 44.7%, respectively. In the multiple-adjusted quantile regression analysis, significant relationships were found between CI ratio and diastolic blood pressure (DBP) (B = 3.76, p = 0.035) and between CRI-2 ratio and DBP (B = 0.005, p = 0.042) and age (B = 0.005, p = 0.031). Conclusions: This study indicated that the majority of studied women had a high risk of CVD based on atherogenic indices. Further public health efforts are required to enhance awareness of women and healthcare providers about preventing and controlling CVD risk.
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Molani‐Gol et al. (2022) conducted a cross-sectional in Cardiovascular disease risk (Dyslipidemia) (n=150). Atherogenic indices and lipid ratios (AIP, AC, CI, CRI-1, CRI-2, non-HDL-C) was evaluated on Association between cholindex (CI) ratio and diastolic blood pressure (DBP) (B = 3.76, 95% CI 2.87-7.24, p=0.035). Atherogenic indices indicated a high risk of cardiovascular disease in the majority of apparently healthy women, with cholindex significantly associated with diastolic blood pressure (B = 3.76).
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