Key result
High waist-to-hip ratio significantly increased the risk of dyslipidemia in southern Iranian women (OR 2.22), alongside age over 45 years and urban residence.
Why the study?
Dyslipidemia is a major global cardiovascular risk factor with known variations in prevalence, prompting an evaluation of dyslipidemia and associated factors in southern Iranian women.
Cross-Sectional (n=2,223)
No
Odds Ratio: 2.22 (95% CI 1.6–3.08)
p-value: p=<0.05
Dyslipidemia is highly prevalent among women in southern Iran, strongly associated with central obesity, advancing age, and urban residence.
May support targeted dyslipidemia screening in centrally obese southern Iranian women; leaves open causal inference and broader validation.
Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted on women from the population-based BKNCD, as part of the Prospective Epidemiological Research Studies in IrAN (PERSIAN). Sociodemographic data, medical history, and anthropometric indices were collected. Dyslipidemia was defined as any lipid abnormality including low-density lipoprotein (LDL) ≥ 160, total cholesterol (TC) ≥ 240, high-density lipoprotein (HDL) < 40, or triglyceride > 200 mg/dl. From the 2223 women in this study (mean age: 48.28 ± 9.26 years), dyslipidemia was observed in 851 (38.3%). High TC was the most common lipid abnormality (18.5%) followed by high LDL (17.7%). Dyslipidemia was most prevalent among women aged 55-70 years, the married, those with < 6 years of education, the unemployed, the overweight or obese, with low socioeconomic status, diabetes, hypertension, and high waist circumference, those using the hookah and living in urban areas. Logistic regression revealed that women with high waist-to-hip ratio (WHR) (OR = 2.22, 95% CI 1.60-3.08), those aged 45-54 years (OR = 1.34, 95% CI 1.07-1.68) and 55-70 years (OR = 1.33, 95% CI 1.03-1.72), and those living in urban areas (OR = 1.35, 95% CI 1.05-1.73) were at significantly increased risk of dyslipidemia. In addition, the results were confirmed using deep neural network models. Dyslipidemia was highly prevalent in Iranian women in the southern coastal region. Central obesity, age over 45 years, and living in urban areas appear to be relatively significant risk factors for dyslipidemia among women.
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Nikparvar et al. (2021) conducted a cross-sectional in Dyslipidemia (n=2,223). High waist-to-hip ratio (WHR) vs. Normal WHR was evaluated on Dyslipidemia (OR 2.22, 95% CI 1.60-3.08, p=<0.05). High waist-to-hip ratio significantly increased the risk of dyslipidemia in southern Iranian women (OR 2.22), alongside age over 45 years and urban residence.
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