Key result
Obstructive sleep apnea was associated with an increased risk of recurrent AF after catheter ablation (OR 1.70; 95% CI 1.40-2.06), whereas CPAP use reduced this risk (OR 0.28; 95% CI 0.19-0.40).
Why the study?
Does continuous positive airway pressure (CPAP) reduce recurrent atrial fibrillation after successful catheter ablation in patients with obstructive sleep apnea?
Population
7 observational studies pooling 4,572 patients with atrial fibrillation who underwent successful…
Comparison
Continuous positive airway pressure therapy in… vs Patients without OSA and OSA patients not using…
Design
Meta-analysis
Authors
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May support CPAP evaluation post-AF ablation in OSA; extends observational associations but leaves causality open pending RCTs.
Meta-Analysis (n=4,572)
Does continuous positive airway pressure (CPAP) reduce recurrent atrial fibrillation after successful catheter ablation in patients with obstructive sleep apnea?
Odds Ratio: 1.7 (95% CI 1.4–2.06)
In patients undergoing successful catheter ablation for atrial fibrillation, untreated OSA increases the risk of AF recurrence, while CPAP therapy significantly reduces this risk.
Congrete et al. (2018) conducted a meta-analysis in Atrial fibrillation after successful catheter ablation (n=4,572). Obstructive sleep apnea (OSA) vs. No OSA was evaluated on Recurrent atrial fibrillation (OR 1.70, 95% CI 1.40-2.06). Obstructive sleep apnea was associated with an increased risk of recurrent AF after catheter ablation (OR 1.70; 95% CI 1.40-2.06), whereas CPAP use reduced this risk (OR 0.28; 95% CI 0.19-0.40).
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