What question did this study set out to answer?

To assess the association between patient gender and long-term cancer-specific survival in individuals surgically treated for glioblastoma multiforme.

October 10, 2018Bioscience ReportsOpen Access

Impact of gender on the survival of patients with glioblastoma

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MTMinjie TianNanjing Brain Hospital WMWenying MaTEDA International Cardiovascular Hospital YCYueqiu ChenSoochow University

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Implication

Population-based cohort study reveals higher five-year survival in female patients with surgically treated glioblastoma, highlighting gender as a critical prognostic factor.

Key Points

To assess the association between patient gender and long-term cancer-specific survival in individuals surgically treated for glioblastoma multiforme.
Extracted population-based data from the SEER database for 6,586 patients diagnosed with glioblastoma between 2000 and 2008 who underwent surgical resection.
Evaluated 5-year cancer-specific survival using Kaplan–Meier methods and multivariable Cox proportional hazards regression models.
The cohort included 6,586 patients (61.5% men, 38.5% women), with 5-year cancer-specific survival rates of 6.8% in men compared to 8.3% in women (P=0.002 by univariate and P<0.001 by multivariate analysis).
Stratified analysis demonstrated that male patients consistently had significantly lower cancer-specific survival across localized disease stages and diverse age subgroups.

Cite This Study

Tian et al. (2018) studied this question.

synapsesocial.com/papers/6a6f1ae526a7f98052dbdab0 https://doi.org/10.1042/bsr20180752

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Implication

Population-based cohort study reveals higher five-year survival in female patients with surgically treated glioblastoma, highlighting gender as a critical prognostic factor.

Impact of gender on the survival of patients with glioblastoma

Discussion

Member takes

Implication

Key Points

Cite This Study

Impact of gender on the survival of patients with glioblastoma

Discussion

Member takes

Implication

Key Points

Cite This Study

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