Key result
Posterior leaflet preservation during mitral valve replacement for rheumatic mitral stenosis did not improve long-term left ventricular ejection fraction compared to excision (67.12% vs 63.66%).
Why the study?
Does posterior leaflet preservation during mitral valve replacement improve long-term left ventricular performance in patients with rheumatic mitral stenosis?
Cohort (n=20)
Does posterior leaflet preservation during mitral valve replacement improve long-term left ventricular performance in patients with rheumatic mitral stenosis?
Absolute Event Rate: 67.12% vs 63.66%
Posterior leaflet preservation during mitral valve replacement for rheumatic mitral stenosis does not significantly improve long-term left ventricular performance or alter hemodynamic valvular characteristics compared to complete excision.
No LVEF benefit seen with preservation in rheumatic MS; leaves open need for RCTs before practice change.
Mitral valve replacement with posterior leaflet preservation was shown beneficial for postoperative left vetricular (LV) performance in patients with mitral regurgitation. Some authors find it beneficial even for the long term LV function. We investigated a long term effect of this technique in patients with rheumatic mitral stenosis. We studied 20 patents with mitral valve replacement due to rheumatic mitral stenosis, in the period from January 1988 to December 1989. In group A (10 patients) both leaflets and coresponding chordal excision was performed, while in group B (10 patients) the posterior leaflet was preserved. In all patients a Carbomedics valve was inserted. We compared clinical pre and postoperative status, as well as hemodynamic characteristics of the valve and left ventricle in both groups. Control echocardiographyc analysis included: maximal (PG) and mean (MG) gradients; effective valve area (AREA); telediastolic (TDV) and telesystolic (TSV) LV volume; stroke volume (SV); ejection fraction (EF); fractional shortening (FS) and segmental LV motion. The mean size of inserted valve was 26.6 in group A and 27.2 in group B. Hemodynamic data: PG (10.12 vs 11.1); MG (3.57 vs 3.87); AREA (2.35 vs 2.30); TDV 126.0 vs 114.5); TSV (42.2 vs 36.62); SV (83.7 vs 77.75); EF (63.66 vs 67.12); FS (32.66 vs 38.25). Diaphragmal segmental hypokinesis was evident in one patient from group A and in two patients from group B. In patients with rheumatic stenosis, posterior leaflet preservation did not have increased beneficial effect on left ventricular performance during long-term follow-up. An adequate posterior leaflet preservation does not change hemodynamic valvular characteristics even after long-term follow-up.
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DJUKIC et al. (2006) conducted a cohort in Rheumatic mitral stenosis (n=20). Posterior leaflet preservation vs. Excision of both leaflets and corresponding chordae was evaluated on Left ventricular ejection fraction (EF). Posterior leaflet preservation during mitral valve replacement for rheumatic mitral stenosis did not improve long-term left ventricular ejection fraction compared to excision (67.12% vs 63.66%).
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